Buprenorphine is a form of opioid that is used to cure opioid use disorder as well as chronic and acute pain. Subutex is the brand name under which buprenorphine is available. Buprenorphine can be used in the cheek, under the tongue, as an implant and even a skin patch.
Buprenorphine treatment commences when the withdrawal symptoms of the opioid disorder begins. Doctors who treat opioid addiction also have the possibilities of adopting medication assisted treatment procedures. The most usual medications used during the treatment of opioid disorder is buprenorphine, naltrexone and methadone. It is very hard for some people to quit the opioid addiction. Therefore, they need help and strong assistance to change the way they behave, think and also replace their surroundings.
A reason why buprenorphine treatment is necessary is because it helps the patients to stay sober while lowering the side effects of withdrawal. It also eradicates any kind of cravings that can lead to relapse.
The buprenorphine treatment was approved by the FDA back in 2002 for treating opioid addicts. This form of treatment does not cause any form of euphoria in the patients and blocks the effects of opioids for at least 24 hours. The success rates have been linked to around 40 to 60% in each study. In order to get treated you don’t have to get admitted to a highly regulated program.
Buprenorphine is the majorly used ingredient in the Suboxone. Beprenorphine is further referred to as partial opioid agonist. Methadone and buprenorphine are both used for the detoxification procedure as well as the opioid replacement therapy. One of the most important things to note is that both of them are quite safe for pregnant women. The buprenorphine treatment is more or less prescribed by a qualified clinician.
There are a few adverse drug reaction effects of taking buprenorphine. Such effects are associated with headache, vomiting, dizziness, drowsiness, cognitive inhibition as well as memory loss.
Buprenorphine is basically a semi synthetic form of thebaine which is pretty much soluble in water. It tends to degrade in the presence of light.
The respiratory effects of buprenorphine treatment include insufficient breathing also known as respiratory depression. This is also common in the people taking alcohol, benzodiazepines or have any kind of lung disease. The common reversal agents of opioid include naloxone. Naloxone has been observed to be partially effective. In order to support breathing additional help is required. Like any other thing buprenorphine can also be a bit dangerous. Buprenorphine is associated with causing some extent of physical or psychological dependence.
Uses of buprenorphine
- Buprenorphine in depression- There is ample evidence that supports the usage of buprenorphine for depressive disorders. Buprenorphine appears to be useful for depression that is treatment resistant.
- Cocaine dependence- Buprenorphine has also been accredited with the treatment of cocaine addiction.
- Neonatal abstinence- Neonatal abstinence syndrome can also be treated with buprenorphine. Neonatal abstinence syndrome is a disorder where newborn babies are exposed to opioids during pregnancy. Infants who are born with this condition are treated with buprenorphine.
- Obsessive compulsive disorder- Individuals with obsessive compulsive disorder are also said to respond well when treated with buprenorphine.
Buprenorphine is available under a lot of trade names in the market. Subutex, suboxone, bunavail, zubsolv, cizdol and sublocade. In many European countries buprenorphine has been introduced as the transdermal formulation. It is primarily used for the treatment of severe pains that do not respond to non-opioids. Buprenorphine treatment is also used as a veterinary medicine that is used to treat pain in cats and dogs.